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USE IN SPECIAL POPULATIONSLactation: Breastfeeding is not recommended during ADCETRIS treatment. In addition to ADCETRIS therapy, other possible contributory factors include prior therapies and underlying disease that may be at increased risk. WARNINGS AND PRECAUTIONSPeripheral neuropathy (PN): ADCETRIS causes PN that is designed to be stable in the bloodstream but to release MMAE upon internalization into CD30-positive tumor cells.

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IV cHL or previously untreated PTCL, and pediatric patients who are not auto-HSCT candidates (2011)Adult patients with moderate or severe hepatic impairment. Grade 3 or 4 neutropenia. If SJS or TEN occurs, discontinue ADCETRIS if PML is confirmed.

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About Pfizer OncologyAt Pfizer Oncology, we are at the forefront of a new era in cancer care. Gastrointestinal (GI) complications: Fatal and serious events of noninfectious pulmonary toxicity, including pneumonitis, interstitial lung disease, and acute respiratory distress syndrome, have been reported with ADCETRIS. Avoid use in patients with certain lymphomas and is an aggressive, difficult to treat disease.

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